Pharmacology ( Paramedic ) Essay Example | Topics and Well Written Essays - 750 words

Pharmacology ( Paramedic ) - Essay Example the incremental cost-effectiveness ratio of Ipilimumab as obtained from a similar research, the cost effectiveness of ipilimumab was found to be $78,218 per life year gained (Barzey et al. 2012, p. 73). This means that the ipilimumab is more cost effective. Adrenergic drugs are the pharmacological compounds that stimulate adrenergic nerves directly. They do this by mimicking the action of epinephrine or adrenaline in the body or stimulating their release. These drugs are used I treatment of life-threatening disorders including asthma, cardiovascular conditions such as cardiac arrest and in allergic reactions. Adrenergic receptors are widely distributed in the body and these drugs act on these receptors. However, their selectivity determines the receptors that the drug group will act on and hence the efficacy and side effects. There are two major groups of adrenergic receptors, which are alpha-receptors and beta-receptors. Those that act selectively on alpha-receptors are associated with constriction of blood vessels especially in the bronchial mucosa and relaxation of gastrointestinal smooth muscles. Those that are beta selective relax bronchial smooth muscles and dilation of bronchi. The beta-adrenoceptors also increase the heart rate and contractility of the heart. This means that using a drug such as salbutamol, which is a beta-adrenergic receptor agonist in asthma will be effective in causing dilation of the bronchi and hence relieve of symptoms. In addition, the drug will cause a considerable increase in heart rate and heart contractility as side effects due to its action on the heart muscles (Baker 2010, pp 1048-1061). The enzyme phosphodiesterase-5 is responsible for the degradation of cGMP in the smooth muscles of small blood vessels especially in the corpus cavernous of the penile shaft. The enzymes are also present in the arterial smooth muscles of the lungs. Inhibitors of this enzyme relieve erectile dysfunction and pulmonary hypertension. Since

Economic Indicators Paper Essay Example | Topics and Well Written Essays - 1250 words

Economic Indicators Paper - Essay Example forms at a level below full employment then monetary and fiscal policy renders a positive impact by increasing employment rather than simply causing inflation or directing the resources towards inefficient use in order to create jobs. Th paper studies the automobile industry with the help of the six economic indicators – real GDP, Unemployment rate, Inflation rate measured by the Consumer Price Index (CPI), Auto Sales, Foreign Exchange Rate and Oil and Fuel Prices. The study focusses essentially on the inflation rate which in turn affects the other indicators as well as the industry and a whole. Real GDP: This is the measure of the total output produced during a specific time period within a certain territory. This is measured at constant prices in order to adjust for the inflation rate. This helps in estimaitng the size of the economy with ajdustment in prices and inflation rates. Unemployment rate: We consider the status of unemployment for a particular individual when he or she is eager to work but is without work. The percentage of the potential labor force who are unemployment is estimated as the unemployment rate. Unemployment is often related to the recessionary phase of an economy or a business cycle. As production falls during recession, in order to cut he cost, labour is retrenched and a sudden unemployment might arise. Inflation rate: This refers to the rate of increase in a certain price index. Usually Consumer Price Index is used to reflect inflation. This is defined as the percentage change in price. level over a certain time period. Conversely, inflation rate is also the decrease in purchasing power of money. With increase in prices purchasing power falls, money supply in the economy rises while the supply or production falls. The automobile industry played an important role in the 1920s when the US economy grew at an accelerated rate creating more and more jobs and income. In the late 1980s, with the increase in competition with the foreign